Stock watchlist – 28 world stock markets with current stock information, intraday stock price, and multiple watchlists.Nina Hallowell is a member of the Wellcome Centre for Ethics and Humanities (Oxford, UK), which is supported by funding from the Wellcome Trust (grant number 203132). In addition, John Norrie acted as a NIHR Journals Library Editor between 20. John Norrie reports grants from the University of Edinburgh (Edinburgh, UK) during the conduct of the study, and is a past and present member of the following: HTA Commissioning Sub-Board (Expressions of Interest) (2012–16), NIHR Clinical Trials Unit Standing Advisory Committee (2017–present), NIHR HTA and EME Editorial Boards (2014–19), Pre-Exposure Prophylaxis Impact Review Panel (2017–present), EME Strategy Advisory Committee (2019–present), EME – Funding Committee Members (2019–present), EME Funding Committee Sub-Group Remit and Competitiveness Check (2019–present), HTA General Committee (2016–19), HTA Funding Committee Policy Group (formerly Clinical Study Group) (2016–19) and HTA Commissioning Committee (2010–16). Last, Dimitrios Siassakos was a member of the HTA Maternal, Neonatal and Child Health Panel (2017–18), HTA Prioritisation Committee C (Mental Health, Women and Children’s Health) (2017–20) and HTA Prioritisation Committee B (In Hospital) (2017–21). In addition, Dimitrios Siassakos reports grants from the NIHR Biomedical Research Centre at University College London Hospitals (London, UK) and non-financial support from Wellcome Engineering and Physical Sciences Research Council Centre for Interventional and Surgical Sciences (London, UK) outside the submitted work. Dimitrios Siassakos reports grants from the NIHR HTA Research for Patient Benefit (reference PB-PG-0817-20046) and HTA programme (references 16/16/06, NIHR127818 and PR-PRU-1217-21202) during the conduct of the study. In addition, Sarah J Stock received other research funding from the NIHR (reference 14/32/01), Wellcome Trust (London, UK) (reference 209560/Z/17/Z) and Chief Scientist Office (London, UK) during the course of the study. Sarah J Stock reports grants from the NIHR HTA programme during the conduct of the study and declares being a member of the NIHR HTA General Committee (2016–21). Julia Lawton was a member of HTA Obesity Themed Call Board (2010) and HTA General Committee (2018–19). In addition, Jane E Norman was a member of the Health Technology Assessment (HTA) Maternal Neonatal and Child Health Panel (2013–18) and was a member of the HTA and Efficacy and Mechanism Evaluation (EME) Editorial Board from 2012 to 2014. Within the last 3 years, Jane E Norman has acted on a Data Safety and Monitoring Board for a study involving a preterm birth therapeutic agent for GlaxoSmithKline plc (Brentford, UK) and has provided consultancy for a small pharma company on drugs to alter labour progress. Specific issues were as follows: different clinicians and participants would be in equipoise for each clinical scenario, effective conduct of the trial would require appropriate resources and expertise within the hospital conducting the trial, potential participants would welcome information on the trial well before the onset of labour and minority ethnic groups would require tailored approaches.ĭeclared competing interests of authors: Jane E Norman has received grants from government and charitable bodies for research into understanding the mechanisms of term and preterm labour and understanding treatments, including research funding from the National Institute for Health Research (NIHR) (references 17/63/08 and 16/151/01). Clear themes around the challenges inherent in conducting any trial emerged, including the concept of equipoise itself. It was agreed that any trial should address the areas with most uncertainty, including the management of women at 26–32 weeks’ gestation, with either spontaneous preterm labour (cephalic presentation) or where preterm birth was medically indicated. The interactive workshop and Delphi consensus process confirmed the need for more evidence (hence the case for a trial) and provided rich information on what a future trial should entail. The parent survey suggested that women and their families generally preferred vaginal birth at later gestations and caesarean section for preterm infants. The clinician survey demonstrated a variety of practice and opinion. There was broad agreement from parents and health-care professionals that a trial is needed. Planned sample size and data saturation was achieved for all groups except for focus groups with participants, as this had to be curtailed because of the COVID-19 pandemic and data saturation was not achieved.
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